Serious, in a negative sense; important, formidable. [from 19th c.]
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Israel’s behaviour is doing grave damage to the Palestinian people and to any hope for peace.
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2016 February 6, James Zogby, “Israel’s prickliness blocks the long quest for peace”, in The National[1]:
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Khrushchev made a grave miscalculation when he failed to appreciate the growing opposition to his power and overestimated the support of his bureaucracy.
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2017, Vladimir Shlapentokh, A Normal Totalitarian Society, page 80: